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Estela Jacinto, Ph.D.

Publications:

  • Oh WJ, Wu C, Kim SJ, Facchinetti V, Julien LA, Finlan M, Roux PR, Su B, Jacinto E. (2010) mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J.
  • Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E. (2008) The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J. 27(14): 1932-43.
  • Jacinto E. (2008) What controls TOR? IUBMBLife 60(8):483-96.
  • Jacinto E, Lorberg A. (2008) TOR regulation of AGC kinases in yeast and mammals. Biochem J. 410(1):19-37.
  • Jacinto E. (2007) Phosphatase targets in TOR signaling. Methods Mol Biol 365:323-34.
  • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. (2006)SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127(1):125-37.
  • Jacinto, E., Loewith, R., Schmidt, A., Lin, S., Ruegg, M.A., Hall, A., and Hall, M.N. (2004). Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biol. 6: 1122-1128.
  • Jacinto, E., and Hall, M.N. (2003). TOR signaling in bugs, brain, and brawn. Nature Reviews (Mol.Cell.Biol) 4, 117-126.Nature Rev (Mol Cell Biol) 4, 117-126.
  • Loewith, R., Jacinto, E., Wullschleger, S., Lorberg, A., Crespo, J.L., Bonenfant, D., Oppliger, W., Jenoe, P., and Hall, M.N. (2002). Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10:457-468.
  • Bonenfant, D., Schmelzle, T., Jacinto, E., Crespo, J.L., Mini, T., Hall, M.N., and Jenoe, P. (2003). Quantitation of changes in site specific phosphorylation: a simple method based on stable isotope labelling and mass spectrometry. PNAS 100:880-885.
  • Jacinto, E., Guo, B., Arndt, K.T., Schmelzle, T., and Hall, M.N. (2001). TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Mol Cell 8:1017-1026.
  • Jacinto, E., Werlen G., and Karin, M. (1998). Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes. Immunity 8:31-41.