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Eric Karl Richfield, M.D., Ph.D.

Present Title:
Associate Professor
Department of Pathology and Laboratory Medicine
07/03 to Present

Office Address:
UMDNJ-Robert Wood Johnson Medical School
One Robert Wood Johnson Place - MEB 212
New Brunswick, NJ 08901

EOHSI
170 Frelinghuysen Road
Piscataway, NJ

Clinical Expertise:
Dr. Richfield performs clinical diagnostic neuropathology.  This includes evaluation of brain and spinal cord biopsies and the postmortem examination of brain and spinal cord.  Forensic and legal cases are also evaluated. 

Research Expertise:
The lab is currently studying pathologic changes in Alzheimer’s and Parkinson’s disease using pre- and
postmortem human tissue.  A variety of tools are used to evaluate clinical grade of disease and pathogenesis including morphological counting and other measurements, immunohistochemistry, and Western blotting. Cerebrospinal fluid and blood are being investigated for use in diagnosis and grading of severity. 

Undergraduate Education:
University of Wisconsin-Milwaukee
Milwaukee, WI
B.S., Applied Math and Physics, Magna Cum Laude
09/71-05/75

Graduate Education:
Medical College of Wisconsin
Milwaukee, WI
Doctor of Medicine
06/75-05/80   

University of Michigan
Ann Arbor, MI
Doctor of Philosophy, Neurosciences
06/83-12/87  
Master of Science, Program in Clinical Research Design and Statistical Analysis
08/88

Postgraduate Training:
St. Joseph's Hospital
Milwaukee, WI
Internship, Department of Medicine
07/80-06/81

University of Michigan
Ann Arbor, MI
Residency, Department of Neurology
07/81-06/84
Fellowship, Department of Neurology/Specialty Training - Movement Disorders
07/84-10/87

National Institute of Mental Health
Unit of Functional Neuroanatomy
Clinical Neuroendocrinology Branch
Washington, DC
11/87-07/89        

University of Rochester School of Medicine and Dentistry
Rochester, NY
Residency, Department of Pathology, Specialty Training – Neuropathology
07/95-06/97

Academic Appointments:
UMDNJ-Robert Wood Johnson Medical School
New Brunswick/Piscataway, NJ
Associate Professor
07/03 to Present

University of Rochester
Rochester, NY 
Associate Professor
Department of Pathology
07/97-06/03
Associate Professor
Department of Pharmacology and Physiology
07/95-6/03
Assistant Professor
Department of Pharmacology and Physiology
07/91-06/95
Assistant Professor
Department of Neurology
07/89-06/95       

Hospital Appointments:
Robert Wood Johnson University Hospital
New Brunswick, NJ
Staff Pathologist
07/03 to Present

University of Rochester Medical Center  
Rochester, NY        
07/89-08/03      

Monroe Community Hospital
Rochester, NY
Chief of Service
Geriatric Neurology Unit
07/93-06/95   

Licensure:
State of Michigan Medical License
State of New York Medical License
State of New Jersey Medical License

Certification:
1981 - Diplomat, National Board of Medical Examiners
1986 - Diplomat in Neurology, American Board of Psychiatry & Neurology Certificate No. 28202
1997 - Diplomat in Neuropathology, American Board of Pathology

Professional Organizations:
Society for Neuroscience
American Association of Neuropathologists, Inc.

Service on UMDNJ Committee:
MD - PhD Admissions Committee

Selected Publications:

  • Nicholas, A, de Magalhaes, J.P., Kraytsberg, Y., Richfield, E.K., Levanon, E.Y., and Khrapko, K. (2010) Age-related gene-specific changes of A-to-I mRNA editing in the human brain.  Mechanisms of Ageing and Development 131: 445-447.
  • Prasad, K. and Richfield, E.K. (2010) Real time epifluorescence stereology and morphology of neurons in
    the mouse substantia nigra and ventral tegmental area.  Experimental Neurology 225:328-340. 
  • Kavita Prasad, Elizabeth Tarasewicz, Pamela A. Ohman Strickland, Michael O’Neill, Stephen N. Mitchell,
    Kalpana Merchant, Samnang Tep, Kathryn Hilton, Akash Datwani, Manuel Buttini, Sarah Mueller-Steiner,
    and Eric K. Richfield. (2011) Biochemical and morphological consequences of human a-synuclein
    expression in a mouse a-synuclein null background. European Journal of Neuroscience European
    Journal of Neuroscience 33:642-656. 
  • Yin, L., Lu, L., Prasad, K., Richfield, E.K., Unger, E., Xu, J., and Jones, B.C. (2011) Genetically-Based
    Differential Susceptibility to Paraquat Neurotoxicity in Mice Neurotoxicology & Teratology (in press).
  • Peneder, T.M., Berger, M., Scholze, P., Heinze, G., Bertl, J., Bauer, J., Richfield, E.K. Hornykiewicz, O., Pifl C. (2011) Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice. Neuroscience (in press).
  • Lipoff, D.M., Bhambri, A., Fokas, G., Sharma, S., Gabel, L.A., Brumberg, J.C., Richfield, E.K., Ramos, R.L.
    (2011) Neocortical Molecular Layer Heterotopia in Substrains of C57BL/6 and C57BL/10 Mice. Brain
    Research  (in press)