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Shengkan (Victor) Jin, Ph.D.



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Selected Publications:

Feng, H., Levine, A. J., and Jin. S. (2005). The Coordinate Regulation of the p53 and mTOR Pathways in Cells. Proc. Nat. Acad. Sci. 102 (23): 8204-8209.

Zhang, H., Monken, C. E., Lenard, J., Mizushima, N., Lattime E. C., and Jin, S. (2006).  Cellular Autophagy Machinery is not Required for Vaccinia Virus Replication and Maturation. Autophagy. 2(2): 91-95.

Levine, A. J., Feng, Z., Tak W. You, M. H., and Jin, S. (2006). Coordination and Communication between the p53 and IGF-1-AKT-TOR Signal Transduction Pathways. Genes and Dev. 20 (3): 267-75.

Degenhardt, K., Mathew, R., Beaudoin, B., Bray, K., Anderson, D, Chen, G., Mukherjee, C., Shi, Y., Gelinas, C., Nelson, D.A., Jin, S., and White, E. (2006). Autophagy Promotes Tumor cell Survival and Restricts Necrosis, Inflammation, and Tumorigenesis. Cancer Cell. 10(1):51-64.

Jin, S. (2006). Autophagy, Mitochondria Quality Control, and Oncogenesis. Autophagy. 2(2): 80-84.

Zhang, Y., Qi H., Taylor, R., Xu, W., Liu, LF., and Jin, S. (2007) Autophagy is required for mitochondria degradation and optimal mitochondrial function in S. cerevisiae. Autophagy. 9;3(4): 337-46

Mathew, R., Konqara, S., Beaudoin, B., Karp, CM., Bray, K., Degenhardt, K., Chen, G., Jin, S., White, E. (2007). Autophagy suppresses tumor progression by limiting chromosomal instability. Genes and Dev. 21(11):1367-81.

Karantza-Wadsworth, V., Patel, S., Kravchuk, O., Chen, G., Mathew, R, Jin, S., White, E. (2007) Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev. 21(13):1621-35.

Jin, S.* and White, E. (2008) Tumor Suppression by Autophagy Through the Management of Metabolic Stress. Autophagy. 2008 Mar 3;4(5) (* Jin, S. is a co-corresponding author)

Baerga, R., Zhang, Y., Chen, P., Goldman, P., and Jin, S. (2009) Targeted Deletion of autophagy-related 5 (atg5) Impair WAT Adipogenesis in a Cell Culture Model and in Mice. Autophagy, 5(8):1118-30.

Zhang, Y., Goldman, S., Baerga, R., Zhao, Y., Komatsu, M., and Jin, S. (2009) Adipose-Specific Deletion of the Autophagy-Related Gene 7 (atg7) Reveals a Role in Adipogenesis. Proc. Natl. Acad. Sci. 106(47):19860-5.

Goldman, S., Zhang, Y., and Jin, S. (2010) Autophagy and adipogenesis: Implications in obesity and type II diabetes.  Autophagy, 6 (1): 179-181.

 

Zhang, Y., Goldman, S., Baerga, R., Zhao, Y., Komatsu, M., and Jin, S. (2009) Adipose-Specific Deletion of the Autophagy-Related Gene 7 (atg7) Reveals a Role in Adipogenesis. Proc. Natl. Acad. Sci. 106(47):19860-5.

 

Goldman, S., Zhang, Y., and Jin, S. (2010) Autophagy and adipogenesis: Implications in obesity and type II diabetes. Autophagy, 6 (1): 179-181.

 

Jin S.  (2011) Mitochondrial complex III: Tuner of autophagy.

Chemistry & Biology. 2011; 18(11):1348-9.

 

Moloughney, JG., Monken, CE., Tao, H., Zhang, H., Thomas, JD., Lattime, EC., Jin, S. (2011)  Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation.  Autophagy. 2011; 7(12):1434-47.

Guidelines for the use and interpretation of assays for monitoring autophagy (2012) Autophagy. 2012; 8(4):445-544.

Taylor, R. Jr, Chen, PH., Chou, CC., Patel, J., Jin, SV. (2012)  KCS1 deletion in Saccharomyces cerevisiae leads to a defect in translocation of autophagic proteins and reduces autophagosome formation.   Autophagy; 8(9):1300-11.

 

Zhang, Y., Zeng, X., Jin, S. (2012)  Autophagy in adipose tissue biology.

Pharmacological research: the official journal of the Italian Pharmacological Society. 66(6):505-12.

 

Tao, H., Taylor, R., Zeng, X., Jin, S. (2013) Autophagy and Cancer.  Wang H, editor. New York: Springer; Role of Autophagy in Tumorigenesis; 95-112p.

My Bibliography

 

Goldman, SJ., Jin, S. (2014) The bioluminescent imaging of spontaneously occurring tumors in immunocompetent ODD-luciferase bearing transgenic mice.  Methods in molecular biology (Clifton, NJ); 1098:129-43.


Tao, H., Zhang, Y., Zeng, X., Shulman, GI., Jin, S. (2014)  Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.  Nature Medicine. 20(11):1263-9.