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News and Events
Graduate Student Research Seminar:

You are invited to the Molecular Biosciences Graduate Student Research Seminar to be held  on Thursday,  October 11, 2018 at 4:00 pm, in the Waksman Room 1001

Presenters:

Vrushank Bhatt - Guo/White Lab

Role of Autophagy in Kras-Driven Non-Small Cell Lung Cancer (NSCLC)

Praveen Bommareddy  - Zloza/Kaufman Lab

Turning Killer into Cure: Utilizing Oncolytic Herpes  Simplex -1 Viruses for Cancer Immunotherapy

 
If you are unable to attend in person and wish to access this meeting remotely, you may use GoToMeeting:

Please join my meeting from your computer, tablet or smartphone. https://global.gotomeeting.com/join/269040413

You can also dial in using your phone. United States: +1 (646) 749-3131
Access Code: 269-040-413

 


Rutgers RWJMS Basic Science Seminar Series:


Emerging Frontiers in Biomedical Research

Tuesday, November 6, 2018

4:00 PM

RWJMS, CABM room 010

Topic: 

The gut microbiome in human nutrition and health


Presenter:

Liping Zhao, PhD

Professor

Eveleigh-Fenton Chair of Applied Microbiology

Department of Biochemistry and Microbiology 

School of Environmental and Biological Sciences 

Rutgers, The State University

of New Jersey

 

 

 


Recent Publications:

 

SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation. 

Chi Kwan Tsang, Miao Chen, Xin Cheng, Yanmei Qi, Yin Chen, Ishani Das, Xiaoxing Li, Brinda Vallat, Li-Wu Fu, Chao-Nan Qian, Hui-Yun Wang, Eileen White, Stephen K. Burley, X.F. Steven Zheng.  2018 Molecular Cell 70, 502-515, May 3 2018

Interview with the Author: https://www.cell.com/molecular-cell/meet-the-author.

To Claim Growth Turf, mTOR Says SOD Off. 

Hyewon Kong and Navdeep S. Chandel. Maintaining redox balance in cancer cells is essential for tumor development and progression. In this issue of Molecular Cell, Tsang et al. (2018) identify an evolutionarily conserved mTORC1-dependent mechanism by which cancer cells control redox homeostasis in ischemic tumor microenvironment. 2018 Molecular Cell 70, 502-515, May 3 2018 

Article preview by Navdeep Chandel: https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30311-3

 

Pyocyanin Inhibits Chlamydia Infection by Disabling Infectivity of the Elementary Body and Disrupting Intracellular Growth.  

Li JL, Yang N, Huang L, Chen D, Zhao Y, Tang MM, Fan H, Bao X.  Antimicrob Agents Chemother. 2018 Apr 2. pii: AAC.02260-17. doi: 10.1128/AAC.02260-17. [Epub ahead of print]

 

Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer.

Amer Alasadi, Michael Chen, G. V. T. Swapna, Hanlin Tao, Jingjing Guo, Juan Collantes, Noor Fadhil, Gaetano T. Montelione and Shengkan Jin.  Cell Death and Disease (2018) 9:215

 

 

Recent Research Grants and Awards:

 

Shengkan "Victor" Jin, Ph.D., Associate Professor, Department of Pharmacology, received TechAdvance Grant in the amount of $100,000. Project title: A Novel Base Editing Technology for Treatment of Genetic Diseases: Proof-of-Concept in Cystic Fibrosis, Gaucher's Disease, and Duchenne Muscular Dystrophy Cell Models.

 

Shengkan "Victor" Jin, Ph.D., Associate Professor, Department of Pharmacology, received R21 award totaling $427,850.  Project Title: Prevention and treatment of ALD by inducing hepatic mitochondrial uncoupling.

Dr. Jin has an ongoing NIH/NCI R21 grant (awarded last year) in amount of $437,250.  Project title: Target cell metabolism for preventing and treating metastatic colon cancer

 

Monica J. Roth, PhD, professor of pharmacology, a five-year, $2,854,055  Maximizing Investigators' Research Award (MIRA) grant for "Targeting Retroviral and Virus-Like Particles for Gene and Protein Delivery."  The coinvestigator is Gaetano T. Montelione, PhD, Jerome and Lorraine Aresty Chair and Distinguished Professor of Biochemistry and Molecular Biology, Rutgers University, and adjunct professor of biochemistry and molecular biology, Rutgers Robert Wood Johnson Medical School.

 

Daniel Herranz Benito, PhD, assistant professor of pharmacology, awarded a grant

in the amount of $100,000.00 for a period of one year from the Leukemia Research Foundation.

 

Daniel Herranz Benito, PhD, assistant professor of pharmacology, received a three-year, Transition Phase R00 Pathway to Independence Award from the NIH totaling $747,000 to explore "Functional Dissection of Oncogenic Enhancers."