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News and Events
Graduate Student Research Seminar:

 

You are invited to the Molecular Biosciences Graduate Student Research Seminar to be held on Thursday, January 18, 2018 at 4:00 pm, in the Waksman Auditorium

Presenters:

TBA

 


If you are unable to attend in person and wish to access this meeting remotely, you may use GoToMeeting:

Please join my meeting from your computer, tablet or smartphone. https://global.gotomeeting.com/join/269040413

You can also dial in using your phone. United States: +1 (646) 749-3131 - Access Code: 269-040-413

 

Rutgers RWJMS Basic Science Seminar Series:

 

Emerging Frontiers in Biomedical Research

 

Tuesday, January 23, 2018

4:00 pm

CABM,  Room  010

 

Topic:

Dynamics of translation

 

Presenter:

Joseph D. Puglisi, PhD
Professor

Department of Structural Biology

Stanford University School of Medicine


 

 

Biomedical Data Science Forum

 

Dr. William Welsh served as an invited panelist at a Biomedical Data Science Forum held on October 25 at Princeton University.  The forum was entitled "Ahead of the Curve: New Frontiers in Biomedical Data Science".

Dr. Welsh presented an invited talk entitled "Overcoming Formulation Challenges in the Era of Biotherapeutics" coauthored by him and his collaborator Herschel (Hersch) Rabitz at Princeton University.

 

Fo more information about the Forum please go to link below: https://www.princeton.edu/news/2017/10/31/mix-biotech-data-science-nj-promising-better-health-and-business-growth-panel

 

Mix of biotech, data science in NJ is promising for better health and business growth, panel concludes

www.princeton.edu

Companies and academic institutions of New Jersey have a unique opportunity to solve health care problems and grow new businesses at the intersection of biotechnology and data science, a panel of leaders from industry and academia concluded at a conference convened by Princeton University on Oct. 25.

 


 

Recent Publications:

 

β-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus.

Ferrer-González E, Kaul M, Parhi AK, LaVoie EJ, Pilch DS.   Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.00863-17. doi: 10.1128/AAC.00863-17. [Epub ahead of print]

 

Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ.

Fujita J, Maeda Y, Mizohata E, Inoue T, Kaul M, Parhi AK, LaVoie EJ, Pilch DS, Matsumura H.

ACS Chem Biol. 2017 Jul 21;12(7):1947-1955. doi: 10.1021/acschembio.7b00323. Epub 2017 Jun 16.

 

Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Kimani SG, Kumar S, Bansal N, Singh K, Kholodovych V, Comollo T, Peng Y, Kotenko SV, Sarafianos SG, Bertino JR, Welsh WJ, Birge RB. Sci Rep. 2017; 7: 43908. Published online 2017 Mar 8. doi: 10.1038/srep43908

 

Repression of the chromatin tethering domain of murine leukemia virus p12. Brzezinski, J. D., Modi, A., Liu, M. and Roth, M. J.; J. Virol  2016 Oct 5. pii: JVI.01084-16: 90 (24), 11197-11207. PMID: 27707926 [Epub ahead of print]

 

Phosphorylation requirement of murine leukemia virus p12.  Brzezinski, J. D., Felkner, R., Modi, A., Liu, M., and Roth, M. J.; J. Virol 2016 Oct 5.; 90 (24), pii: JVI.01178-16. 11208-11219. PMID: 27707931 [Epub ahead of print]

 

X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus Integrase and its implications for viral DNA recognition. Guan, R., Aiyer, S., Cote, ML, Xiao, R.,1 Jiang, M., Acton, T. B., Roth, M. J., Montelione, G. T. 2016. ; Proteins: Structure, Function, and Bioinformatics,; in press.

 

Prevention of Obesity and Type 2 Diabetes with Aged Citrus Peel (Chenpi) Extract.
Jingjing Guo, Hanlin Tao, Yong Cao, Chi-Tang Ho, Shengkang Jin, and Qingrong Huang
.
J. Agric. Food Chem., 2016, 64 (10), pp 2053–2061

 

Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus.

Kaul M, Mark L, Parhi AK, LaVoie EJ, Pilch DS. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4290-6. doi: 10.1128/AAC.00613-16. Print 2016 Jul.

 

Arginine-and Polyamine-Induced Lactic Acid Resistance in Neisseria gonorrhoeae. Gong Z, Tang MM, Wu X, Phillips N, Galkowski D, Jarvis GA, Fan H.  PLoS One. 2016 Jan 25;11(1):e0147637. doi: 10.1371/journal.pone.0147637. eCollection 2016.

 

Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe.  George AA, Walworth NC.  Genetics. 2015 Oct 28. 201:1467-78. pii: genetics.115.181792. .  [Epub ahead of print]

 


Recent Research Grants and Awards:

 

Daniel Herranz Benito, PhD, assistant professor of pharmacology, received a three-year, Transition Phase R00 Pathway to Independence Award from the NIH totaling $747,000 to explore "Functional Dissection of Oncogenic Enhancers." 

 

William Welsh, PhD, Norman H. Edelman Professor in Bioinformatics, Department of Pharmacology, was granted a $100,000 award from TechAdvance to facilitate commercialization of Rutgers Technologies for his First-in-Class Pan-TAM Tyrosine kinase inhibitors for cancer therapy.

 

Jerome Langer, PhD, associate professor of pharmacology, and Beatrice Haimovich, PhD, associate professor of surgery, received a five-year, R25 multi-PI research education program grant for $2,365,247 from the National Institutes of Health for the "Rutgers Initiative for Maximizing Student Development (IMSD) Pipeline Program." The grant will extend the impact of the program, founded in 1996, allowing the team to build on the experience and successes in research training of under-represented minority students, and increase the number of Rutgers undergraduate and graduate students from diverse backgrounds who continue into careers in biomedical research and who eventually will assume leadership roles in the field.