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Pintar, John E. Ph.D.
Photograph of John Pintar, PhD

PhD, University of Oregon, 1977

Phone: (732) 235-4250
: (732) 235-4990

Research Interests
Developmental neurobiology and endocrinology; genetic studies of systems controlling growth, metabolism, responses to analgesics, and adaptation to environmental stress.

Selected Publications: For complete list PubMed

Cominski TP, Turchin CE, Hsu MS, Ansonoff MA, Pintar JE. Loss of the mu opioid receptor on different genetic backgrounds leads to increased bromodeoxyuridine labeling in the dentate gyrus only after repeated injection.
Neuroscience. 2012 Mar 29;206:49-59. Epub 2012 Jan 16. PubMed PMID: 22280973.

Majumdar S, Grinnell S, Le Rouzic V, Burgman M, Polikar L, Ansonoff M, Pintar J, Pan YX, Pasternak GW. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19778-83. Epub 2011 Nov 21. PubMed PMID: 22106286.

Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE. The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation. J Neurochem. 2010 Mar 26. [Epub ahead of print] PubMed PMID: 20367757.

Ansonoff MA, Portoghese PS, Pintar JE. Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands. Psychopharmacology (Berl). 2010 Jun;210(2):161-8. Epub 2010 Mar 24. PubMed PMID: 20333506.

Ansonoff MA, Wen T, Pintar JE. Kappa2 opioid receptor subtype binding requires the presence of the DOR-1 gene. Front Biosci (Schol Ed). 2010 Jan 1;2:772-80. PubMed PMID: 20036983.

Czyzyk TA, Nogueiras R, Lockwood JF, McKinzie JH, Coskun T, Pintar JE, Hammond C, Tschop MH, Statnick MA. kappa-Opioid receptors control the metabolic response to a high-energy diet in mice. FASEB J. 2010 Apr;24(4):1151-9. Epub 2009 Nov 16. PubMed PMID: 19917675; PubMed Central PMCID: PMC2845433.

Ning, Y, Conover, C., Pintar, J..E. (2008). IGPBP-4 is both a positive and negative regulator of IGF in vivo, Mol. Emdocrinol. 22:1213-25.

Zhu, Y., King, M., Schuller, A., Nitsche, J., Reidl, M., Elde, R., Pasternak, G.W. and Pintar, J.E. (1999). Retention of supraspinal delta-like analgesia and loss of morphine tolerance in DOR-1 knock-out mice. Neuron, 24:1-10.

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