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Research News
By Kate O’Neill
Research Grants
The National Institutes of Health awarded grants of $1 million or more to the following members of the Robert Wood Johnson Medical School faculty: • M. Maral Mouradian, MD, William Dow Lovett Professor of Neurology and director, Center for Neurodegenerative and Neuroimmunologic Diseases, a three-year, $1,333,897 R21 grant for “Developing Novel RNA-Based Therapeutics for Parkinson’s Disease.” • Nancy E. Reichman, PhD, professor of pediatrics, a $1,166,852 grant for “Effects of Maternal Work Incentives on Adolescent Social and Health Behaviors.” • Derek B. Sant’Angelo, PhD, Harold L. Paz, MD, Endowed Professor of Developmental Biology, professor of pediatrics, and chief, division of developmental biology, Child Health Institute of New Jersey, increased funding for a five-year, now $2,385,000 R01 grant for “Contribution of Innate-like Tregs for Preventing Tissue Inflammation.” Grants of $1 million or more from other funding sources included two additional awards: • Eugene Martin, PhD, professor of pathology and laboratory medicine, a $1,839,568 grant from the New Jersey Department of Health for “AIDS17CTN018‒Rapid HIV Testing Support.” • Arnold B. Rabson, MD, Laura Gallagher Endowed Chair of Developmental Biology, professor of molecular genetics, microbiology, and immunology, pathology and laboratory medicine, and pediatrics, and director, Child Health Institute of New Jersey, a four-year, $5,000,000 grant from the Robert Wood Johnson Foundation for “Supporting the Child Health Institute of New Jersey as a Comprehensive Biomedical Research Center.”
Published Research
The following is a representative sample of articles by Robert Wood Johnson Medical School researchers recently published in leading biomedical journals: • Nadia D. Ali, MD, a fellow in the Department of Medicine, was first author of “Charcot-Leyden Crystals in T-cell Lymphoblastic Lymphoma,” published in Blood 2017:129(3):394. (Epub ahead of print.) David J. Weissmann, MD, associate professor of pathology and laboratory medicine, was senior author of the article. • Melinda S. Borrie, a graduate fellow working in the laboratory of Marc R. Gartenberg, PhD, professor of biochemistry and molecular biology and director, Graduate Program in Cellular and Molecular Pharmacology, was first author of “Binding, Sliding, and Function of Cohesin during Transcriptional Activation,” published in the Proceedings of the National Academy of Sciences of the United States of America 2017. (Epub ahead of print.) Dr. Gartenberg was senior author of the article. • Yanxiang (Jessie) Guo, PhD, assistant professor of medicine and resident member, Rutgers Cancer Institute of New Jersey, was first author of “Autophagy Provides Metabolic Substrates to Maintain Energy Charge and Nucleotide Pools in Ras-Driven Lung Cancer Cells,” published in Genes and Development 2016:30(15):1704‒1717. • In addition, Dr. Guo was a coauthor of “Autophagy, Metabolism, and Cancer,” published in Cold Spring Harbor Symposia on Quantitative Biology: Epub February 18, 2017. • Shawna V. Hudson, PhD, associate professor and director, research division, Department of Family Medicine and Community Health, was senior author of “Integrating Primary Care Providers in the Care of Cancer Survivors: Gaps in Evidence and Future Opportunities,” published in the Lancet Oncology: Epub January 5, 2017:8(1):e30‒38. • Joseph Moloughney, PhD, a postdoctoral fellow in the laboratory of Estela Jacinto, PhD, associate professor of biochemistry and molecular biology, was first author of “mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1,” published in Molecular Cell 2016:63(5):811‒826. Dr. Jacinto was senior author of the article. • Sabin Motwani, MD, assistant professor of radiation oncology and member, Rutgers Cancer Institute of New Jersey, was first author of “Hypofractionated Radiotherapy for Prostate Cancer,” published in the Lancet Oncology 2016:17(12):e517. • Naomi Schlesinger, MD, professor of medicine and chief, division of rheumatology and connective tissue research, was the author of “Crystal Arthritis: New Recommendations Highlight the Need for More Research,” published in Nature Reviews Rheumatology 2016:12(11):628‒630. • Yufang Shi, DVM, MSc, PhD, University Professor of Pharmacology and member, Child Health Institute of New Jersey, was first author of “Tumour-Associated Mesenchymal Stem/Stromal Cells: Emerging Therapeutic Targets,” published in Nature Reviews Drug Discovery 2017:16(1):35‒52. • Josh Vieth, PhD, a postdoctoral appointee in the laboratory of Derek B. Sant’Angelo, PhD, Harold L. Paz, MD, Endowed Professor of Developmental Biology, professor of pediatrics, and chief, division of developmental biology, Child Health Institute of New Jersey, was first author of “TCR alpha-TCR beta Pairing Controls Recognition of Cd1d and Directs the Development of Adipose Nkt Cells,” published in Nature Immunology 2017:18(1):36‒44. Dr. Sant’Angelo was senior author of the article. • In addition, “AKA,” a poem by Zeynep Uzumcu, MD ’17, was published in the Journal of the American Medical Association 2017:317(5):539. M
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