News Release - January 26, 2011

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Jennifer Forbes                                                                                                         
Communications & Public Affairs
732-235-6356, jenn.forbes@umdnj.edu

 

                                                                           

Study of Multiple Asthma Triggers in Children of Urban Communities
Earns $1.2m Grant from Environmental Protection Agency

 

View Dr. Laumbach's appearance on NJN News HealthwatchLaumbach_R

Piscataway, NJ -- A newly announced study by researchers at UMDNJ-Robert Wood Johnson Medical School will examine how elevated levels of exposure to air pollutants, coupled with chronic psychological stress, may contribute to higher rates of asthma in urban communities.  The study, supported by a $1.2 million grant from the Environmental Protection Agency, will focus on children in the Ironbound section of Newark, NJ, one of the most asthma-prevalent areas in the state.  Residents of Newark have disproportionately high rates of hospitalizations and emergency room visits as a result of asthma attacks according to the New Jersey Department of Health and Senior Services.

During the next four years, the research team will evaluate 40 Ironbound children between the ages of 9 and 14 who have mild to moderate persistent asthma.  Led by Robert Laumbach, MD, MPH, assistant professor of environmental and occupational medicine at Robert Wood Johnson Medical School, the researchers will evaluate numerous asthma triggers in children – exposure to multiple air pollutants caused by the area’s severe traffic congestion and the effect of chronic stress that results from socioeconomic circumstances.

Under typical conditions, the body naturally responds to an asthma attack in an attempt to reduce its severity. However, the investigators believe that elevated chronic stress conditions within urban communities, such as poverty or violence, inhibit the body’s ability to cope, thereby creating a more severe asthma attack for children in these areas. According to Dr. Laumbach, the combined effects of air pollution and stress may be one reason why asthma hospitalization is four times greater in children who live in some urban communities.

The Ironbound section of Newark is bordered by the New Jersey Turnpike, state Routes 1&9, Interstate 78, Newark Liberty International Airport, and the Ports of Newark and Elizabeth.  The high density of diesel trucks, ships, port equipment, airplanes, and cars in this area causes higher concentrations of soot and other air pollutants in the air. 

The researchers will measure a child’s individual exposure to air pollutants for 24-hours-a-day for four weeks using digital devices clipped to his or her clothing.  By comparing air pollution exposure to periodic daily measurements of breathing capacity, the researchers will assess the impact of air pollution on asthma. The researchers also will evaluate the effect of stress conditions within the children’s lives through interviews with participant families and measurement of stress hormones, in order to determine whether or not those children with higher stress levels have more severe responses to air pollution. 

The team includes six investigators from the Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ-Robert Wood Johnson Medical School and Rutgers, The State University of New Jersey, and members of the Ironbound Community Corporation, the neighborhood’s leading social services agency, which will participate in conducting the study.

 

About UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL

As one of the nation’s leading comprehensive medical schools, UMDNJ-Robert Wood Johnson Medical School is dedicated to the pursuit of excellence in education, research, health care delivery, and the promotion of community health. In cooperation with Robert Wood Johnson University Hospital, the medical school’s principal affiliate, they comprise New Jersey’s premier academic medical center. In addition, Robert Wood Johnson Medical School has 34 other hospital affiliates and ambulatory care sites throughout the region.

As one of the eight schools of the University of Medicine and Dentistry of New Jersey with 2,800 full-time and volunteer faculty, Robert Wood Johnson Medical School encompasses 22 basic science and clinical departments, hosts centers and institutes including The Cancer Institute of New Jersey, the Child Health Institute of New Jersey, the Center for Advanced Biotechnology and Medicine, the Environmental and Occupational Health Sciences Institute, and the Stem Cell Institute of New Jersey. The medical school maintains educational programs at the undergraduate, graduate and postgraduate levels for more than 1,500 students on its campuses in New Brunswick, Piscataway, and Camden, and provides continuing education courses for health care professionals and community education programs.  To learn more about UMDNJ-Robert Wood Johnson Medical School, log on to rwjms.umdnj.edu. Find our fan page at www.Facebook.com/RWJMS and follow us on Twitter www.twitter.com/UMDNJ_RWJMS.

 

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