Jonathon Walsh, Ph.D.
Department of Genetics,
Life Sciences Building, Piscataway, NJ
2012 B.S. Biology – Georgia Southern University, Statesboro, GA
2012 B.S. Chemistry – Georgia Southern University, Statesboro, GA
2018 PhD. Genetics – The University of Georgia, Athens, GA
2018 – Present INSPIRE Postdoctoral Fellow, Department of Genetics – Rutgers University, Piscataway, NJ
Research Mentor: Maureen Barr, PhD
Research Topic: Investigation of Polycystin function in C. elegans as a model for studying mechanisms of Autosomal Dominant Polycystic Kidney Disease (ADPKD). My research is focused on revealing the distinct and cooperative functions of the polycystins in cilia and extracellular vesicles (EVs).
Teaching Mentor: William Carr, D.V.M., PhD. Medgar Evers College. Brooklyn, NY.
Teaching Interests: General, Cell, and Molecular Biology, Genetics, Developmental Biology, General Chemistry.
Kade M. Power, Jyothi S. Akella, Amanda Gu, Jonathon D. Walsh, Sebastian Bellotti, Margaret Morash, Winnie Zhang, Yasmin H. Ramadan, Nicole Ross, Andy Golden, Harold E. Smith, Maureen M. Barr, Robert O’Hagan. Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function. PLOs Genetics. 2020. (provisionally Accepted)
What about the males? the C. elegans sexually dimorphic nervous system and a CRISPR-based tool to study males in a hermaphroditic species. (Invited review/methods) Walsh JD, Boivin O, Barr MM. J Neurogenetics. 2020 Jul 10:1-12.
Development of a method for revertable CRISPR/Cas9-based mutagenesis in cell culture. Jonathon Walsh and Jonathan Eggenschwiler. BioRxiv. September 2020.
Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice. Snouffer A, Brown D, Lee H, Walsh J, Lupu F, Norman R, Lechtreck K, Ko HW, Eggenschwiler J. PLoS Genetics. 2017 Aug 17;13(8):e1006912.
IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium. Wingfield JL, Mengoni I, Bomberger H, Jiang YY, Walsh JD, Brown JM, Picariello T, Cochran DA, Zhu B, Pan J, Eggenschwiler J, Gaertig J, Witman GB, Kner P, Lechtreck K. Elife. 2017 May 31;6:e26609.
Using CRISPR/Cas9 genome editing technology as an educational tool to study primary cilia in mammalian cell culture. Jonathon Walsh, Brian Condie, Karl Lechtreck, Jonathan Eggenschwiler. CUREnet collection. 2018.