Xiaoyang Su, PhD

Links

https://scholar.google.com/citations?user=Kw2aFXcAAAAJ&hl=en&oi=ao

https://orcid.org/0000-0001-8081-1396

Affiliations & Leadership

• Department of Medicine, Division of Endocrinology, Co-Director of Metabolomics Shared Resource of RCINJ, (2023-Present)

Education and Training

• B.S. in Biology, Tsinghua University, Beijing, China (2004)
• M.S. in Chemistry, Tsinghua University, Beijing, China (2007)
• Ph.D. in Chemistry and Chemical Biology, Cornell University, Ithaca, USA (2013)

Research/Clinical Interests and Description

Dr. Su has strong expertise in the design, data acquisition, result interpretation, and data visualization of LC-MS metabolomics experiments, especially in the stable-isotope labeling studies.

Active research and clinical projects

Su Lab is applying its expertise in LC-MS metabolomics to study the biochemical function of orphan solute carrier (SLC) transporters. Su Lab developed a metabolomic-transcriptomic association analysis workflow, which revealed the biochemical function of uncharacterized SLC transporters. Using the stable isotope tracing strategy, Su Lab is studying the cellular metabolite direct uptake and de novo synthesis quantitatively.

Publications

• Metabolic Flux Analysis-Linking Isotope Labeling and Metabolic Fluxes. Wang Y, Wondisford FE, Song C, Zhang T, Su X. Metabolites. 2020 Nov 6;10(11):447. doi: 10.3390/metabo10110447. PMID: 33172051
• Metabolite Spectral Accuracy on Orbitraps. Su X, Lu W, Rabinowitz JD. Anal Chem. 2017 Jun 6;89(11):5940-5948. doi: 10.1021/acs.analchem.7b00396. PMID: 28471646
• Chemical Basis for Deuterium Labeling of Fat and NADPH. Zhang Z, Chen L, Liu L, Su X, Rabinowitz JD. J Am Chem Soc. 2017 Oct 18;139(41):14368-14371. doi: 10.1021/jacs.7b08012. Epub 2017 Oct 4. PMID: 28911221

Biography Link:

https://www.ncbi.nlm.nih.gov/myncbi/1R7T8dKyqrpswh/bibliography/public/