minimum commitment as an instructor of yeast
genetics and genomics at Cold Spring Harbor
days or longer during the extent of the course, combining lec-
tures and hands-on experimental techniques. Dr. Gartenberg
says his particular expertise in the area of microscopy com-
plemented the skills of the course's other main instructors:
Grant W. Brown, PhD, professor of biochemistry, University
of Toronto, who specializes in genomics; and Maitreya
Dunham, associate professor of genome sciences, University
of Washington, and formerly a Lewis-Siglar Fellow at
Princeton University, whose strength is evolutionary biology.
Their lectures and experimental work were supplemented by
nearly two dozen guest lecturers who are counted among the
leaders in their respective fields, Dr. Gartenberg notes.
Virginia School of Medicine. Dr. Smith was once a graduate
student of Dr. Gartenberg's colleague Monica J. Roth, PhD,
Gartenberg jokes. "I did not calculate how satisfying it would
be to essentially pass along 20 years of knowledge in the field
in such a short period of time. Throughout those three weeks,
you can watch the lightbulbs go on as students start to under-
stand techniques, get new ideas. You just know they're going
to do great things one day. It's very satisfying to have played
a role in some way in that growth."
planning to begin using yeast in their lab for research; post-
doctoral students who are using yeast for the first time; and
techniques involved--from the most basic methods to the lat-
est ones--and disseminate them to scientists in their own labs.
receive their "marching orders," outlining the program and
experiments planned for the day. A one-hour lecture on a topic
return to work on the day's modules. At 4 p.m., a guest lecturer
gives a two-hour talk devoted to his or her area of expertise.
experiments for the rest of the evening, if needed. Although no
and teaching assistants are available for questions and assistance
with those modules every evening, often until later than 1 a.m.
any given day, Dr. Gartenberg says. Multiply that work over
the 21 days of the course, and it's easy to see how it has been
back and forth, and things really begin to crystallize," he says.
at Robert Wood Johnson Medical School. "What I
learned the first time I was an instructor for this
eukaryotic--in other words, each cell con-
within a cell membrane. Yeast cells share many genes
in common with human cells and are easily adapted to
genetic analysis, making them ideal as a representative
model of all eukaryotic cells.
to use in research:
known, making them the first eukaryotic microorganism
whose genome has been entirely characterized.
tain more than 1,000 genes whose human counterparts are
linked to human diseases).
biology, genetics, and biochemistry.
the opportunity to attend the three-week intensive course on
principles and practices of yeast research at Cold Spring Harbor