Hiroko Nobuta, PhD

Hiroko Nobuto is an assistant professor at the Department of Neuroscience and Cell Biology and serves as resident faculty at the Center for Advanced Biotechnology and Medicine.

The major goal of her research is to develop regenerative therapies for human oligodendrocyte disorders such as leukodystrophies, multiple sclerosis, and white matter injury associated with premature birth. Her lab takes two approaches to achieve the goal: gaining fundamental knowledge in human brain development and engineering transplantable human oligodendrocytes.

Current funding: Career Transition Award, National Multiple Sclerosis Society

Education

• PhD in Neuroscience, University of California Los Angeles, 2012
• Postdoc, University of California San Francisco and Stanford University, 2012-2018, Albert Einstein College of Medicine, 2018-2020

• Nobuta H, Yang N, Ng YH, Marro SG, Sabeur K, Chavali M, Stockley JH, page1image181885840DW, Walter PB, Zhao C, Huie P, Goldman SA, Kriegstein AR, Franklin RJM, Rowitch D, Wernig M. Cell Stem Cell. 2019 Oct 3;25(4):531-541. Human Oligodendrocyte Death in Pelizaeus-Merzbacher Disease is Rescued by Iron Chelation.
• “Next Generation Human Disease Models in Neuroscience.” A faculty presenter at virtual conference for the Society for Neuroscience. Viewable at https://neuronline.sfn.org/Articles/Scientific-Research/2019/Next-Generation-Human-Disease- Models-in-Neuroscience. Sep 2019.
• “Generation of Oligodendrocytes from iPS Cells: Stem Cells and Reprogramming Methods for Neuroscience.” A faculty presenter at the Online Training Series for the Society for Neuroscience. Viewable at https://neuronline.sfn.org/. Aug 2019.