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Bio

John Pintar is a Professor at the Department of Neuroscience and Cell Biology. He received his PhD from the University of Oregon and completed his post-doctorate training at Yale.

Publications and More

Selected Publications

  • Schuller, A. G.P. King, M., Zhang, J., Bolan, E., Pan, Y-X., Morgan, D.J., Chang A., Czick, M.E., Unterwald, E., Pasternak, G W. and Pintar. J.E. (1999). Retention of heroin and morphine-6 glucuronide analgesia in a new line of MOR-1 knockout mice insensitive to morphine: Nature Neuroscience 2:1-8.
  • Zhu, Y., King, M., Schuller, A., Nitsche, J., Reidl, M., Elde, R., Pasternak, G.W. and Pintar, J.E. (1999). Retention of supraspinal delta-like analgesia and loss of morphine tolerance in DOR-1 knockout mice. Neuron 24:243-252.
  • Ning Y, Schuller AG, Bradshaw S, Rotwein P, Ludwig T, Frystyk J, Pintar JE. (2006).Diminished Growth and Enhanced Glucose Metabolism in triple knock out mice containing mutations of insulin like-growth factor binding proteins -3, -4, and -5.Mol Endocrinol. 2006 May 4; [Epub ahead of print]
  • Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE. (2010). The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation. J Neurochem. 2010 Mar 26. [Epub ahead ofprint] PubMed PMID: 20367757.
  • Chen YC, Mains RE, Eipper BA, Hoffman BG, Czyzyk TA, Pintar JE, Verchere CB (2020. PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.  Diabetologia. 2020 Mar;63(3):561-576. doi: 10.1007/s00125-019-05060-z. Epub 2020 Jan 27. PMID: 31984442
  • Akgün E, Lunzer MM, Tian D, Ansonoff M, Pintar J, Bruce D, Hawkinson JE, Wilcox GL, Portoghese PS. (2020) FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer. Biochemistry. 2020 Sep 20. doi: 10.1021/acs.biochem.0c00498. Online ahead of print. PMID: 32930576
  • Faouzi A, Uprety R, Gomes I, Massaly N, Keresztes AI, Le Rouzic V, Gupta A, Zhang T, Yoon HJ, Ansonoff M, Allaoa A, Pan YX, Pintar J, Morón JA, Streicher JM, Devi LA, Majumdar S. J
  • Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.  Med Chem. 2020 Nov 25;63(22):13618-13637. doi: 10.1021/acs.jmedchem.0c00901. Epub 2020 Nov 10. PMID: 33170687

Current funding

NIH, BHI, Rutgers Internal Idea Grant ORED