Subhajyoti De, PhD
Associate Professor
Bio
Subhajyoti De completed his BS in engineering from the Indian Institute of Technology, Kharagpur, India before pursuing a PhD from the University of Cambridge, UK in the laboratory of Prof. Sarah Teichmann. There, he developed computational biology approaches to study genetic variations and mutational signatures associated with human genome evolution. As a Human Frontier Science Program Fellow in the group of Prof. Franziska Michor at Harvard University, Dr. De investigated cancer as a somatic evolutionary process. He demonstrated that genetic and epigenetic abnormalities in cancer genomes show non-random, context-dependent patterns.
Dr. De and his lab is the cancer genomics and systems biology group at Rutgers CINJ. They develop new methods and work in close collaboration with bench scientists and clinicians on relevant projects. Their research includes genomic instability in cancer, regulatory alterations in cancer, evolutionary dynamics of cancer, and somatic mutations in benign human tissues.
In his independent laboratory, first at Univ. Colorado and currently at the Rutgers Cancer Institute of New Jersey, Dr. De is investigating cancer as a complex, adaptive system using genomic, computational, and systems-level approaches. He is a recipient of the NIH/NCI PSOC Trans-network Young Investigator Award and the Webb-Waring Scholar Award. The NIH, United Against Lung Cancer Foundation, and Boettcher Foundation have supported his work.
His research interests include, single molecule sequencing, evolutionary dynamics of tumor, genomic instability, and non-coding mutations in cancer.
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