Clemow L (PI):“SCORE (Special Care Outreach, Evaluation) to increase the impact of Behavioral Health Integration at FMMS”, Horizon Blue Cross-Blue Shield of New Jersey. $150,000 [each year]; 1/1/2017 – 12/31/2020.
The purpose of this project is to study the impact of special outreach efforts for psychosocial evaluation and primary care-based treatment and case management for a group of patients in a large primary care practice. The intervention participants will be compared with matched controls from the insurer's patient database to compare healthcare costs.
Crabtree BF (PI): “PCMH Implementation Strategies: Implications for Cancer Survivor Care” R01 CA176545, NCI. $1,227,374 [direct], $678,083 [indirect], $1,905,457 [total]; 9/1/2014 – 12/30/2018 (No Cost Extension).
The Patient-Centered Medical Home (PCMH) is a promising model that many hope will significantly improve the way primary care is delivered in the US; however, the ability of a PCMH to deliver the complex care required for cancer survivors is not known. Practice transformation to a PCMH is a lengthy and challenging process and the actual implementation process is poorly understood. This project seeks to identify and describe the impact that fundamentally different dominant goals for becoming a PCMH have on cancer survivor care. Results will provide guidance to states, health plans, and policymakers on PCMH implementations.
Crabtree BF (PI): (Subcontract) with Oregon Health & Science University (Cohen:PI)
Agency for Healthcare Research and Quality (AHRQ), RFA-HS-14-0909 “Evaluating System Change to Advance Learning and Take Evidence to Scale (ESCALATES)”.
Subcontract $1,424,377 [direct], $840,382 [indirect], $2,264,759 [total], 5/1/2015 – 4/31/2019
Evaluating System Change to Advance Learning and Take Evidence to Scale (ESCALATES) is a study to evaluate the R18s funded by AHRQ through RFA-HS-14-008. In this study, we will engage R18 grantees in the overall evaluation by harmonizing measures and working together on data collection and analysis, identify the practice, organization and contextual factors among the combined 2000 practices that are associated with higher and lower levels of deliver of ABCS at baseline (prior to any intervention), identify which intervention strategies implemented by R18 grantees are most effective at improving delivery of ABCS services and practice quality improvement capacity over time and in relation to practice, organization and contextual factors, and identify why some strategies are more effective. We will engage, rapidly disseminate, and evaluate the impact of disseminating actionable findings to key external stakeholder. The lessons from the ESCALATES study will inform other D&I efforts of various sizes in the US, and accelerate the evidence-based practice change critical for improving the quality, sustainability and patient-centeredness of healthcare.
Davis S (PI) Ferrante JM ( Co-I): “Clearing the Air: An Exploratory Qualitative Study to Identify the Knowledge, Attitudes and Beliefs about Low Dose CT among NJ Primary Care Providers,”ScreenNJ, Cancer Institute of New Jersey. $100,000 [total], 07/1/18-06/30/19
This qualitative study explores the knowledge, attitudes, and beliefs surrounding lung cancer screening with low dose CT scanning to help understand implementation challenges of lung cancer screening in diverse populations.
Delnevo C (MPI), Hudson SV (MPI): “ Adoption, diffusion and implementation of Tobacco 21 policies to address health disparities”, R01CA231139, NCI. $1,865,647 [direct], $1,171,532 [indirect], $3,037,179 [total requested], 07/01/2018-06/30/2023. *** Scored 15, 1st percentile***
Using the multiple streams policy and RE-AIM implementation science frameworks, this project uses a mixed methods approach to understand the implementation and impact of policies that raise the minimum legal access to tobacco age to 21, seeking to expand the evidence base with a focus on racial/ethnic groups in the context of a diverse tobacco environment. Specifically, we: (1) carry out a comparative case study of 15 states using document analysis of Tobacco 21 bills, news media content analysis, and key informant interviews to identify factors that may contribute to the adoption or rejection of Tobacco 21 legislation; (2) conduct a repeated cross sectional tobacco product purchase study to examine implementation of a statewide Tobacco 21 law in New Jersey; and, (3) describe the impact of Tobacco 21 laws by modeling tobacco use behavior among 13 to 25 year olds in states with and without Tobacco 21 laws using data from the National Survey on Drug Use and Health.
Demissie K (PI), Crabtree BF (Co-I): “A comparative effectiveness study of locoregional treatments for hepatocellular carcinoma”, PCORI. $2,080,000 [direct], $2,795,000 [total], 1/1/2019 – 12/31/2021
The overarching goal of the proposed study is to conduct a comparative effectiveness (CE) analysis of locoregional treatments (LRT) -- transarterial chemoembolization (TACE), transarterial radioembolization with Yttrium-90 (TARE), bland transarterial embolization (TAE), and thermal ablation (TA) among patients with intermediate-staged hepatocellular carcinoma (HCC). The specific aims are: (1) Compare overall survival (OS) and liver cancer-specific survival (LCS) among patients who were treated with either TACE, TARE, TAE, or TA; (2) Compare time-to-progression among the four LRT groups; (3) Compare rates of receipt of liver transplant or surgical resection (as proxy for successful tumor downstaging) among patients who were treated with TACE, TARE, TAE, or TA; (4) Compare side effects and complication rates among the four LRTs; and (5) Identify patient and physician factors associated with treatment choices..
Ferrante JM (PI), Hudson SV (Co-I), Steinberg M (Co-I), Kinney A (Co-I) : “ ScreenNJ Resource and Evaluation Unit,” Cancer Institute of New Jersey. $234,897 [total], 11/1/18-10/31/19.
This project will function as both a resource and evaluation center for the ScreenNJ colorectal and lung cancer screening projects. The Unit will: 1) provide scientific expertise regarding CRC and lung cancer screening; 2) develop the evidence base for locally developed CRC and lung cancer screening strategies among diverse populations in New Jersey; and 3) facilitate coordination and collaboration among the different ScreenNJ screening programs.
Hudson SV (PI): “Speeding Research-tested INTerventions (SPRINT): EXCELS,” National Cancer Institute via VentureWell. $15,000 [direct], $6,750 [indirect], $21,750 [total], 01/01/2018-12/30/2018
Using the EXCELS intervention platform (R01CA176838) our team will participate in an elite think-tank with 10 other NCI funded research groups from across the US in an innovation ecosystem for behavioral interventionists. Funded by the National Cancer Institute, the SPRINT program provides real world, hands-on training on how to transform research innovations in cancer control into market-ready products and services.
Hudson SV (PI): “Extended Cancer Education for Longer-term Survivors (EXCELS) in Primary Care,” R01 CA176838, NCI, $2,352,240 [direct], $883,172 [indirect], $3,235,412 [total], 9/30/2013 – 08/31/2019 (No Cost Extension).
This research will develop and test a highly innovative, self-management intervention based on social-cognitive theory and health communication best practices, as well as on smart technology for ready access to patients. The EXCELS intervention will consist of (1) enhanced education and decision support materials delivered via mobile web and smart phone application and (2) health coach/care manager engagement. This research should inform the design of programs to enhance patient activation and engagement in their follow up care and thereby improve cancer surveillance and disease prevention
Hudson SV (PI): “Extended Cancer Education for Longer-term Survivors (EXCELS) in Primary Care,” Re-Entry Supplement 1R01 CA176838-01A1, NCI. $84,129 [direct], $49,636 [indirect], $133,765 [total], 09/01/2014 – 08/31/2019 (No Cost Extension).
The supplement will capture critical data, utilizing interview methodology, by systematically assessing and addressing awareness, needs and behaviors of overweight/obese BCS. Further, data collected will support and extend the utility of the EXCELS parent grant by providing data on the needs of a high risk subset of patients, overweight/obese BCS. Insights from the supplement will be used to (1) extend the candidate’s expertise - broadening her knowledge in new areas of study (cancer prevention and control, mobile health [mHealth]) and training in the use of qualitative research techniques that are essential to behavioral intervention development, design and implementation; (2) inform the refinement and enhancement of a novel, mHealth intervention proposed in the EXCELS parent grant; and (3) provide preliminary data for the candidate’s planned K award application to develop a theory-driven, mHealth intervention to promote a healthy lifestyle among overweight/obese women after a breast cancer diagnosis.
Hudson SV (PI): “Extended Cancer Education for Longer-term Survivors (EXCELS) in Primary Care,” Diversity Supplement R01 CA176838-03, NCI. $211,476 [direct], $124,770 [indirect], $336,246 [total], 07/01/2016 – 06/30/2019 (No Cost Extension).
This diversity supplement will take advantage of a unique opportunity to allow the candidate, Dr. Stacy Davis, to examine the relation between health literacy and technology ownership and usage among a large and diverse sample of cancer survivors in the Northeastern United States. Results of this analysis will provide valuable guidance on the development of technology-based interventions for diverse cancer survivors. Aims of the study are: 1) describe the socio-demographic characteristics, including health literacy, of cancer survivors surveyed in the parent grant and compare estimates to other national health surveys and US census data; 2) describe the type and extent of technology ownership and usage among cancer survivors in the parent grant and compare these estimates to other national surveys; and, 3) examine associations of technology ownership and usage and socio-demographic characteristics, including health literacy among cancer survivors in the parent grant.
Lee HS (PI), Hudson SV (Co-I), Bradley KA (Co-I). “ Assessing the Needs of Primary Care Patients and Clinicians for Opioid Use Disorder (OUD) Medication Decisions” to PA-16-161 NIH Exploratory/Developmental Research Grant Program (Parent R21). $275,000 [direct], $162,250 [indirect], $437,251 [total], 04/1/2018 – 3/31/2020.
High-quality patient-centered medical care involves shared decision making between patients and providers. This study will conduct qualitative interviews to learn about the needs of patients with OUDs and providers to develop a patient-centered intervention to increase and enhance patient choice of evidence-based, medication treatment for OUDs in a future grant.