Active Grants

Crabtree BF (PI), Hudson SV (Co-I), Cantor J (Co-I): (Subcontract) with University of Southern California Tsui J (PI), “Accelerating Evidence-based Strategies into Practice for HPV Vaccination in Safety-Net Primary Care Settings,” R37CA242541, NCI. $750,000 [direct], $1,192,500 [total], 08/20/2020 – 04/30/2024. 

This research is identifing multilevel stakeholder perspectives on existing evidence-based strategies (EBS) targeted at the provider, clinic, and system levels and evaluate the implementation of EBS to increase HPV vaccination among adolescents (males and females) within safety-net primary care settings in New Jersey.

Delnevo C (MPI), Hudson SV (MPI): “Adoption, diffusion and implementation of Tobacco 21 policies to address health disparities,” R01CA231139, NCI.  $1,865,647 [direct], $1,171,532 [indirect], $3,037,179 [total], 07/01/2018 – 06/30/2023. 

Using the multiple streams policy and RE-AIM implementation science frameworks, this project uses a mixed methods approach to understand the implementation and impact of policies that raise the minimum legal access to tobacco age to 21, seeking to expand the evidence base with a focus on racial/ethnic groups in the context of a diverse tobacco environment. Specifically, we: (1) carry out a comparative case study of 15 states using document analysis of Tobacco 21 bills, news media content analysis, and key informant interviews to identify factors that may contribute to the adoption or rejection of Tobacco 21 legislation; (2) conduct a repeated cross sectional tobacco product purchase study to examine implementation of a statewide Tobacco 21 law in New Jersey; and, (3) describe the impact of Tobacco 21 laws by modeling tobacco use behavior among 13 to 25 year olds in states with and without Tobacco 21 laws using data from the National Survey on Drug Use and Health.


Ferrante JM (PI).
“Lung Cancer Screening at FMMS,” CINJ/NJ Department of Health, $115,409 [direct], $115,409 [total], 07/01/2021 – 06/30/2022. 

The goal of this project is to increase lung cancer screening in primary care using patient and provider education, outreach, and patient navigation.


Heckman C (PI), Hudson SV (Co-I).  “A Multi-Level Investigation of US Indoor Tanning Policy Enactment, Implementation, Compliance, Impact, and Economics,” R01CA244370, NCI.  $2,953,004 [direct], $830,535 [indirect], $3,783,539 [total], 07/01/2020 – 06/30/2025. ***Impact Score 17, 2nd percentile***


The goals of this 5-year R01 are to use a mixed-method approach informed by the Multiple [Policy] Streams (MSF) and RE-AIM, Frameworks to investigate the following Specific Aims related to policy adoption, implementation (e.g., compliance), and maintenance (i.e., sustainability) to guide policy efforts and decrease IT prevalence.

Hudson (MPI), Crabtree (MPI), “Adapting and implementing evidence-based breast cancer follow-up,” R01CA257197, NCI. $3,919,583 [total], 07/01/2021 – 06/30/2026.

Using a blended implementation/primary care practice change conceptual framework, this project aims to: (1) engage diverse primary care stakeholders in identifying actionable, practice-based activities for provision of long-term breast cancer survivorship care in primary care using depth interviews; (2) prioritize, synthesize, and identify actionable activities for providing care to long-term cancer survivors in primary care by engaging key stakeholders using modified online Delphi methods and concept mapping; and (3) implement and evaluate actionable breast cancer survivorship symptom and risk management activities using a hybrid type 1 effectiveness-implementation cluster study design with waitlist control in 26 primary care practices

Jimenez M (PI), Crabtree BF (Co-I), and Hudson SV (Co-I), "Addressing Disparities in Language and Social-emotional Skill Acquisition using Multi-Level Strategies in Primary Care,” R01HD099125, NICHD. $3,637,203 [total], 05/15/2020 – 02/28/2025. 

This 3-arm randomized clinical trial (RCT) is testing strategies designed to address these barriers using individual and community level interventions. We will recruit 630 parent-child dyads from community health centers that serve low-income, Latino families. Parents will be randomly assigned to one of 3 arms (1) A standard evidence-based literacy promotion intervention that is widely disseminated (2) Literacy promotion plus tailored outreach text messages; (3) Literacy promotion plus tailored outreach text messages and material hardship screening with linkage to community-based resources (multi-level strategy).

Jimenez ME (PI), Crabtree BF (Co-I), and Hudson (Co-I), “Ready and Healthy for Kindergarten: A Primary Care Innovation to Promote a 360-degree View of Child Health," R18HS028574, AHRQ. $1,986,472 [total], 9/30/2021 - 08/31/2026.

This study tests an innovative family wellness program that promotes academic and physical readiness for school among Latino dual language learners using a rigorous mixed methods and community engaged approach.

Kinney AY (PI), Hudson SV (Co-I) Ganeson, S (Co-I): “Promoting INformed approaches in Precision Oncology and ImmuNoTherapy (PINPOINT). Pfizer Global Medical Grants” (overseen by the American Cancer Society) Addressing Racial Disparities in Cancer Care. $399,892 [total], 01/01/2021 – 12/31/2022.

Promoting INformed approaches in Precision Oncology and ImmuNoTherapy (PINPOINT) assesses knowledge, attitudes, beliefs, and sociocultural, clinical, and system-level factors that may explain why Black men and women diagnosed with cancer are less likely to receive molecular testing of tumors and precision oncology treatment and participate in clinical trials. Using this information, the team will engage community stakeholders and patient advocates to develop and test an innovative, patient-centered and culturally tailored internet-based education and decision support intervention. This project is one of 10 funded nationwide.

Luth, EA (PI). “Enhancing Dementia Instruction and Tool in Home Hospice (EDITH-HC),” R00AG065624, NIA. $746,200 [total], 09/01/21-08/31/24.

This study develops and pilot tests an educational intervention and support tool for hospice nurses and social workers to reduce stress and burden in family care partners of home hospice patients living with dementia.

Manne S (PI), Hudson SV (Co-I), "Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survivor Trial,"  R01CA240344, NCI. $3,729,269 [total], 03/15/2020 – 02/28/2025.

This single site clinical trial study is to evaluate the impact of Empowered Survivor against a Generic Online intervention on the primary outcomes of self-efficacy in managing care, preparedness for managing survivorship, and health-related QOL.

Nguyen AM (PI). "Evaluation of the COVID-19 Emergency Reciprocity Licensure Program in NJ," Culture of Health, Robert Wood Johnson Foundation. $35,000 [total], 01/01/2021 – 12/31/2021.

In response to the COVID-19 pandemic, the State of New Jersey enacted the Emergency Reciprocity Licensure Program, allowing out-of-state healthcare practitioners to obtain temporary licensure and provide services to NJ patients via telehealth or in-person. In partnership with the NJ Office of the Attorney General's Division of Consumer Affairs, this 3-part study is exploring the impact of the Program on access to care in NJ and draw lessons for future licensure policies.

Nguyen AM (PI), “Trends in Medicaid Cancer Screening in the COVID-19 Pandemic and Identification of Best Practices,” ScreenNJ $99,035 [total], 07/01/2021 – 06/30/2022.

The goals of this proposed mixed methods study are to produce and disseminate actionable evidence on: 1) the effects of the COVID-19 pandemic on cancer screening rates among New Jersey Medicaid recipients, and 2) best practice strategies to improve cancer screening rates among New Jersey Medicaid beneficiaries overall and in times of public health emergencies.  The study uses comprehensive, longitudinal New Jersey Medicaid enrollment, claims and encounter data through December 2020 (more current if available) augmented with qualitative interviews with provider organizations.

O’Malley D (PI), “Optimizing Colorectal Cancer Screening among Patients with Diabetes in Safety-Net Primary Care Settings: Targeting Implementation Approaches,” K99CA256043-01/R00, NCI. $1,063,928 [total], $1,040,452 [total direct], $23,476 [indirect], 12/01/2020 – 11/30/2025. 

Patients with diabetes diagnosed with colorectal cancer are at high risk for excess morbidity and mortality and are disproportionately Non-Hispanic Black and Hispanic. Federally qualified health centers, who primarily serve priority populations, struggle to implement and sustain colorectal cancer screening. This study will identify and overcome multi-level factors affecting optimal use of CRC preventive screening options for patients with elevated medical and social risks throughout the U.S. 

O'Malley DM (PI), Kinney AY (Mentor). "Developing Implementation Approaches to Target Colorectal Cancer Screening among Patients with Diabetes in Safety-net Primary Care Settings", Robert E. Leet and Clara Guthrie Patterson Trust Mentored Research Award and Seery Clinical Investigator Award Program. $90,000 [total], 01/31/2020 – 01/30/2023.

The Patterson Trust Award provides support to conduct a mentored research project to identify and overcome multi-level (e.g., patients, health system) factors that affect the optimal use of colonoscopy for high risk patients (e.g., T2DM). The proposed research will identify and overcome multi-level factors affecting optimal use of CRC preventive screening options for patients with elevated medical and social risks throughout the U.S.

Panettieri R (PI), Core C. Project Leads: Hudson SV and Tallia A (C. Community and Collaboration) Core Advisor Crabtree BF, NJPCRN lead Ferrante JM. “National Institutes of Health, New Jersey Alliance for Clinical and Translational Science: NJ ACTS,” UL1TR003017, NCATS. $645,968 [core direct], 03/11/2019-02/29/2024.

The Community and Collaboration Core of NJ ACTS enhances and encourages community engagement and team science that will address critical health and healthcare issues in the population of New Jersey.  Our community engagement strategies consist of: (1) engaging community stakeholders in research by developing and providing infrastructure to connect and train NJ academic and community partners and creating a technical assistance core for stakeholder engaged translational science; and, (2) facilitating knowledge transfer regarding innovative community engagement methods and practices.

Panettieri R (PI), RADxUP Supplement MPIs: Hudson SV (contact PI), Barrett E, Blaser M, Hill D, Jimenez M.  “National Institutes of Health, New Jersey Alliance for Clinical and Translational Science (NJ ACTS): NJ HEROES TOO,” 3UL1TR003017-02S2, NCATS. $5,000,000 [total], 09/01/2020 – 02/29/2024.

NJ HEROES TOO (New Jersey Healthcare Essential WoRker Outreach and Education Study - Testing Overlooked Occupations) is engaging Black and Latinx NJ minority communities in Essex, Union, Passaic, and Middlesex counties in COVID-19 testing by providing access to home based saliva testing for their households and extended families. We will compare outreach to families of healthcare workers with a community based organization outreach strategy.

Zhao L (PI), Policastro P (Co-I), Lam Y (Co-I), Ferrante J (Co-I), Keith I (Co-I), Wu G (Co-I): "Targeting the Foundation Guild of Gut Microbiota for Remission of Type 2 Diabetes" New Jersey Institute for Food, Nutrition, and Health. $222,000 [total], 10/01/2019-09/30/2021.

This randomized clinical trial uses intensive microbiota-targeted interventions to restore and maintain the foundation guild of acetate and butyrate producers in patients with T2DM and test for their effects on achieving clinically relevant remission of T2DM. This main trial is supported by a food and culinary technology development study to increase the effectiveness and applicability of a high-fiber dietary regimen to restore and maintain the foundation guild. We are also testing the feasibility of using an in vitro fermentation system for personalized fiber prescription for higher efficiency and specificity of modulating the gut microbiota using dietary fibers.